Annu Rev Cell Biol 9:129–161. Inactivation of a cell-surface receptor depends on: both the binding affinity of the receptor and concentration of ligand surrounding the cell. 1990. both the binding affinity of the receptor and concentration of ligand surrounding the cell. 1991. Evans PD, Robb S, Cheek TR, Reale V, Hannan FL, Swales LS, Hall LM, and Midgley JM. J Biol Chem 272:2363–2372. Lohse MJ, Benovic JL, Caron MG, and Lefkowitz RJ. 1995. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments. Yu SS, Lefkowitz RJ, and Hausdorff WP. Monaghan DT, Bridges RJ, and Cotman CW. Not logged in Trends Biochem Sci 19:548–553. 283:1–19. Although there are important exceptions, hormones, neurotransmitters, and paracrinen substances do not directly enter their target cell surface. Over 10 million scientific documents at your fingertips. C R Seances Acad Sci Paris D 290:567–569. 6:1317–1322. Neuron 6:53–60. A collection of reviews on signal transduction in the journal, © Springer Science+Business Media New York 1999, Introduction to Cellular Signal Transduction, https://doi.org/10.1007/978-1-4612-1990-3_2. Proc Natl Acad Sci USA 87:7722–7726. Annu Rev Biochem 62:453–481. G-Protein-coupled receptor kinases. 1990. Oxford University Press: New York. J Biol Chem 262:16314–16321. TGF-β-receptor-mediated signaling. Ligand-induced internalization of epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitu-tively internalized receptors. 2009 Mar;35(3):281-8. doi: 10.1007/s10886-008-9577-1. Molecular cloning and amino acid sequence of rat enkephalinase. HHS Delineation of the endocytic pathway of substance P and the seven transmem-brane domain NK1 receptor. Downregulation of neutral endopeptidase (EC 3.4.24.11) in the inflamed rat intestine. 1994. A receptor is activated when it binds a signal molecule, and the activated receptor becomes a catalyst or attracts other proteins to it that serve as catalysts in bringing about the desired intracellular changes in the biochemical activity of the cell. Coexistence of guanylate cyclase and atrial natriuretic factor receptor in a 180-kD protein. J Biol Chem 268:337–341. Pitcher J, Lohse MJ, Codina J, Caron MG, and Lefkowitz RJ. 2017 Nov 15;144:63-77. doi: 10.1016/j.bcp.2017.08.002. Cell 73:321–334. both the binding affinity of the receptor and concentration of ligand surrounding the cell. Multiple pathways of rapid β. Lu B, Figini M, Gepetti P, Grady EF, Gerard NP, Ancel JC, Payan DG, Gerard C, and Bunnett NW. Proc Natl Acad Sci USA 83:1174–1178. The control of microvascular permeability and blood pressure by neutral endopeptidase. Barak LS, Menard L, Fergusson SS, Colapietro AM, and Caron MG. 1995. Since the binding of tumor necrosis factor-alpha, interleukin-8, complement factor 5a as well as epidermal growth factor to target cells was dramatically reduced, the inhibition was not receptor or cytokine specific. J Biol Chem 267:2437–2442. Biochem Biophys Res Commun 144:59–66. These observations are not unique to pheophorbides and can be extended to porphyrins as well as to other photodynamic agents. COVID-19 is an emerging, rapidly evolving situation. J. Neurochem 63:400–412. Mechanisms of desensitization and resensitization of G-protein-coupled neurokinin 1 and neurokinin 2 receptors. J Cell Biol 112:469–478. Cheng J, Li W, Tan G, Wang Z, Li S, Jin Y. Biomed Pharmacother. | 109–123. Inactivation of cell surface receptors by pheophorbide a, a green pigment isolated from Psychotria acuminata. Cell 39:283–293. Bohm SK, Grady EF, and Bunnett NW. Biochemical properties of acetylcholine receptor subunits from Torpedo Californica. Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction. Wrana JL, Attisano L, and Wieser R. 1994. Ziemiecki A, Harpur AG, and Wilks AF. 1974. Proc Natl Acad Sci USA 90:5359–5363. Weill CL, McNamee MG, and Karlin A. Get the latest research from NIH: https://www.nih.gov/coronavirus. What effect would vanadate have on the response of cells to signals received by receptor kinases? 1991. Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and PDGF β-receptor. Agonist-specific coupling of G-protein-coupled receptors to second messenger systems. Nature 287:734–736. An Introduction to Molecular Neurobiology. the binding affinity of the receptor. J Biol Chem 269:17056–17061. Pleiotropic role for GRKs and β-arrestins in receptor regulation. Download preview PDF. Biochem J. Phospholipase C-gamma 1 and phosphatidylinosi-tol 3 kinase are the downstream mediators of the PDGF receptor’ mitogenic signal. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. In vitro mutagenesis and the search for structure-function relationships among G-protein coupled receptors. Levitan IB and Kaczmarek LK. Membrane guanylate cyclase is a cell surface receptor with homology to protein kinases. J Biol Chem 263:4993–4996. 1997. 1989. 1991. What causes the inactivation of a G protein? 1995. 1980. This service is more advanced with JavaScript available, Introduction to Cellular Signal Transduction Inactivation of a cell-surface receptor depends on: the activity of phosphatases in the cytosol the concentration of ligand surrounding the cell. Irwin B. Levitan and Leonard K. Kaczmarek. Savarese TM and Fraser CM. USA.gov. Desensitization of the isolated β2-adrenergic receptor by β-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms. Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and PDGF β-receptor. Hanover JA, Willingham MC, and Pastan L.1984. This is a preview of subscription content. 1990. 1984. Inactivation of a cell-surface receptor depends on: Please choose the correct answer from the following choices, and then select the submit answer button. Cell and molecular biology. Nakajima Y, Tsuchida K, Negishi M, Ito S, and Nakanishi S. 1992.
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